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  1. Origin and Evolution of the Gene Family of ... - Oxford Academic

    Sep 22, 2020 · Here, we report the origin and evolution of the ESP gene family. ESP genes were found only in the Muridea and Cricetidae families of rodents, suggesting a recent origin of ESP …

  2. Distinct Genes with Similar Functions Underlie Convergent Evolution

    Aug 8, 2024 · Abstract Convergence offers an opportunity to explore to what extent evolution can be predictable when genomic composition and environmental triggers are similar. Here, we …

  3. Evolutionary Scenarios of Notch Proteins | Molecular Biology

    Apr 15, 2009 · In the Notch1 clade, we observe that the fish possess two Notch1 proteins, whereas in the other clades (Notch2 and Notch3), fish have only one member. In addition, …

  4. Diverse Origins of Near-Identical Antifreeze Proteins in Unrelated …

    Aug 30, 2024 · These findings highlight the diverse evolutionary pathways through which a novel functional gene with convergent sequences at the protein level can evolve across divergent …

  5. Evolution is not Uniform Along Coding Sequences | Molecular Biology

    Feb 28, 2023 · Abstract Amino acids evolve at different speeds within protein sequences, because their functional and structural roles are different. Notably, amino acids located at the …

  6. How Pairwise Coevolutionary Models Capture the Collective …

    Jan 17, 2018 · In the course of evolution, proteins may substitute the vast majority of their amino acids without losing their three-dimensional structure and their biological functionality.

  7. Evolution of Multimeric Protein Assemblages | Molecular Biology

    Dec 5, 2011 · Although the mechanisms by which complex cellular features evolve constitute one of the great unsolved problems of evolutionary biology, it is clear that the emergence of new …

  8. Conserved Ribosomal Protein Has Entirely Dissimilar Structures in ...

    Nov 21, 2023 · Abstract Ribosomes from different species can markedly differ in their composition by including dozens of ribosomal proteins that are unique to specific lineages but absent in …

  9. Evolution of Conjugation and Type IV Secretion Systems

    Sep 13, 2012 · The best-studied system is the vir operon (MPF T) from A. tumefaciens Ti plasmid. This small operon encodes 11 VirB proteins (Thompson et al. 1988; Ward et al. 1988), and we …

  10. Structural Phylogenetics with Confidence | Molecular Biology

    Apr 17, 2020 · For evaluating the deepest evolutionary relationships among proteins, sequence similarity is too low for application of sequence-based homology search or phylogenetic …