The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...
At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, particularly in tissues such as the bone marrow, intestine and skin; neurons and heart ...
A groundbreaking study suggests that if we could eliminate aging mechanisms, humans could potentially live between 146 to 194 years. Researchers spotlight somatic mutations as key contributors to ...
Repetitive sequences make extrachromosomal DNA vulnerable to breaks, which could be exploited for therapy — but might also promote tumour evolution.
Induced pluripotent stem cells have become one of the most powerful tools in modern biomedical research, offering scientists ...
UC San Diego structures show E. coli RNA polymerase reads four synthetic DNA letters the same way it reads the natural four.
A new Viewpoint in eClinicalMedicine argues that immune checkpoint inhibitors have not yet proven they can replace pelvic ...
The Okazaki Fragments That Solved the Mystery of DNA Replication1. The Mystery That Could Not Be Solved by the Discovery of ...
My books are available as e-books. I would be very grateful if you could read them. I am also on X, so I would be very happy ...
New modelling suggests how compartmentalised cross-catalysing networks can evolve adaptations that are passed on through ...
BACKGROUND: Epigenetic mechanisms underlying susceptibility to abdominal aortic aneurysm (AAA) remain poorly understood.
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