A tumor suppressor gene known as p53 is mutated in more than half of all cancers, but how it acts to prevent cancer formation ...

New research shows that pathogenic variants in the chromatin regulator MSL2 disrupt oligodendrocyte precursor cell division ...

Researchers at the University of Washington have successfully reconstructed the lineage of 1.28 million cells in a developing mouse embryo using ...

Myxobacteria are renowned producers of structurally diverse bioactive natural products but are difficult to engineer. Here the authors create a robust heterologous expression chassis and develop ...

Repetitive sequences make extrachromosomal DNA vulnerable to breaks, which could be exploited for therapy — but might also promote tumour evolution.

Direct conversion of human blood cells into neural stem cells erases nearly all epigenetic age over a protracted fifty-day ...

Radiation therapy starts damaging cancer cells during treatment, but most cells do not die immediately. Radiation works ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations. When ...

Cells made from non-living materials have consumed food and divided.Attempts to create cells artificially have been ongoing ...

Mount Sinai team finds that loss of p53 can also change how growth and tissue development signals are organized across a ...

Researchers have discovered that loss of the tumor suppressor p53 allows populations of mutant cells to expand and colonize ...

A body of research suggests that the key to longevity might lie in your morning brew: caffeine. In a 2025 study, researchers ...