Cancer Discov (2026) 16 (10): OF1.
AbstractSingle-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cancer. However, identifying meaningful disease states from single-cell data remains challenging due to the ...
Summary. Neoadjuvant chemoimmunotherapy improves outcomes in resectable non–small cell lung cancer, yet pathologic response incompletely predicts the durability of benefit. Spatial profiling using ...
Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...
Abstract. Pancreatic ductal adenocarcinoma (PDAC) is characterized by early metastatic dissemination and poor clinical outcomes. Although SMAD4 is frequently altered in PDAC, the majority of tumors ...
Abstract. Advances in cancer prevention, early detection, and treatment have led to substantial improvements in cancer outcomes in the United States over the past several decades. Despite this ...
AbstractImmune checkpoint blockade (ICB) has revolutionized cancer treatment, yet its efficacy in gastrointestinal malignancies is often limited by an immunosuppressive tumor microenvironment. In this ...
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