Whole-exome sequencing of liver transplant patients with hepatocellular carcinoma has identified a 13-gene mutation signature ...

An analysis of multiple cancer types has revealed mitochondrial DNA copy number as a key determinant of mutational load and ...

A Phase 3 trial of firmonertinib did not meet its main goal in a hard-to-treat lung cancer subtype, though the drug caused ...

Why do some people develop cancer while others, exposed to seemingly similar environments and living comparable lifestyles, ...

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene ...

For decades, cancer research has focused heavily on genetic mutations, but another theory argues that abnormal chromosome numbers may play a much bigger role than previously recognized. The idea dates ...

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study ...

Risk assessment in mantle cell lymphoma (MCL) is evolving beyond traditional clinical scores, as genomic and dynamic ...

PMV Pharmaceuticals is rated Buy, targeting $3–$4/share, driven by Rezatapopt's 46% response rate. Click to read more about ...

A family history of cancer can affect your risk, but genetics are only part of the picture. Learn when testing or additional ...

Researchers at Fred Hutch Cancer Center have identified a previously overlooked molecular regulator that helps determine ...

Found in 70 percent of cancers, the gene is seen as a grand orchestrator but has been surprisingly difficult to stop.