For decades, cancer research has focused heavily on genetic mutations, but another theory argues that abnormal chromosome numbers may play a much bigger role than previously recognized. The idea dates ...

Why do some people develop cancer while others, exposed to seemingly similar environments and living comparable lifestyles, ...

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers such as ...

Lung cancer is so closely associated with smoking that people who have never smoked may assume their risk is extremely low. But new research has identified a rare inherited genetic mutation that ...

A Phase 3 trial of firmonertinib did not meet its main goal in a hard-to-treat lung cancer subtype, though the drug caused ...

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study ...

Found in 70 percent of cancers, the gene is seen as a grand orchestrator but has been surprisingly difficult to stop.

A family history of cancer can affect your risk, but genetics are only part of the picture. Learn when testing or additional ...

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene ...

A single sperm donor who carries a rare cancer-causing genetic mutation has fathered at least 197 children across 14 countries in Europe, according to a collaborative investigation by 14 European news ...

Amivantamab plus chemotherapy demonstrates durable benefit with a differentiated approach that dual targets EGFR and MET1Median overall survival reached 34.3 months with the amivantamab-based regimen, ...