Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments ...

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. Study: ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Researchers reckon it could dramatically accelerate understanding of how DNA influences disease, cancer, and drug discovery.

Google DeepMind's new model deciphers how hidden DNA changes drive disease, predicting gene regulation effects with high ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...

DeepMind’s AlphaGenome AI model could help solve the problem of predicting how variations in noncoding DNA shape gene ...