The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

Researchers at the Cancer Epigenetics Institute (CEI) at Fox Chase Cancer Center have discovered how to control and stop the amplification of MYC—one of the most commonly altered cancer genes linked ...

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate ...

Over decades, researchers have focused on the epigenetic control of DNA-templated processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification, and noncoding RNAs modulate ...

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of ...

The genome is a fascinating place, consisting of complex loops of DNA that are transcribed into RNA, which is translated into protein. However, DNA expression is controlled by factors beyond the ...

Six epigenetic features define the new Epigenetic Hallmarks of Cancer, an add-on to the widely accepted Hallmarks of Cancer. Scientists concluded that malignant transformation requires some degree of ...

Researchers at the Cancer Epigenetics Institute (CEI) at Fox Chase Cancer Center have discovered how to control and stop the amplification of MYC ...

Metabolic diseases such as obesity, fatty liver, and insulin resistance are rapidly increasing worldwide, but fundamental methods to regulate the process of fat formation remain limited. In particular ...

A team of environmental health researchers has uncovered fresh evidence that chemicals routinely encountered during pregnancy ...