Dipa Kamdar does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

Physicians prescribe drugs on the basis of the characteristics of the medications and on the probability that reliable and reproducible clinical effects will result. However, differences in drug ...

Medical researchers used neutron analysis to better understand a protein implicated in the replication of HIV, the retrovirus that causes AIDS. The enzyme, known as HIV-1 protease, is a key drug ...

Induction of cytochrome P450 (CYP) by drugs is one of major concerns for drug-drug interactions. Thus, the assessment of CYP induction by novel compounds is a vital component in the drug discovery and ...

Scientists have solved a 40-year-old puzzle about the mysterious process by which a critical enzyme metabolizes nutrients in foods and chemicals in drugs such as Tylenol, caffeine and opiates. The ...

High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in ...

A drug currently prescribed to treat a rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes simplex 2 viruses, according to a new study published in the journal Science Advances ...

Modafinil — a drug used for sleep disorders and ADHD — can reduce the effectiveness of certain types of birth control. Any medication can come with side effects. But modafinil, also known as Provigil, ...