While physicians and scientists have long known that Alzheimer's disease involves the buildup of toxic protein fragments in ...

Brain cells are constantly swallowing material from the fluid that surrounds them—signaling molecules, nutrients, even pieces of their own surfaces—in a process known as endocytosis that is essential ...

Researchers have identified a protein that links brain immune activity, metabolism, and amyloid clearance, suggesting a new ...

Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein (APP) for the potential treatment of Alzheimer ...

Scientists have found that the anti-seizure medication levetiracetam prevents the buildup of faulty amyloid-beta proteins in ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

The study found that by using this ultrasound technology on test mice, a 75% memory function was fully restored.

Aη, or A-eta, made an initial splash when scientists reported that these fragments of amyloid precursor protein—products of a heretofore unknown cleavage—dampen neural activity. But how? The story ...

Cerebrospinal fluid (CSF) is a clear and watery liquid that flows in and around the brain and spinal cord. Its functions include protecting parts of the nervous system, delivering nutrients and ...

This is a preview. Log in through your library . Abstract Cleavage and release of membrane protein ectodomains, a regulated process that affects many cell surface proteins, remains largely ...